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Promotion Of Second Intention Wound Healing By Emu Oil Lotion:
Comparative Results With Furasin, Polysporin, And Cortisone.
MJ Politis
A Dmytrowich
Department of
Medical Physiology
University of Saskatchewan, Saskatoon, Canada.
Previous studies showed that twice-daily application
of emu oil lotion (mixture of emu oil/fat, vitamin E, and botanical oil)
immediately after creation of full-thickness skin defects delayed wound
healing 6 days later, perhaps owing to its anti-inflammatory actions. If
administration was delayed for 48 hours, a two-fold promotion of wound
contraction, epithelialization, and infiltration of organized granulation
tissue was observed. In the present study, emu oil lotion was applied to
full-thickness skin defects in rodents 24 hours after surgery. Six days
postoperatively, wound contraction and infiltration of fronts of
epithelialized and granulation tissues were assessed. Results indicated a
two-fold promotion of all of the above parameters with emu oil lotion. No
such effects were exerted by pure emu oil, furasin, cortaid, or polysporin.
Data obtained indicate promise for emu oil lotion as an aid in treating
full-thickness skin defects if applied after the major postinflammatory
stages of wound healing have transpired.
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